Sentence examples for be relevant for substrate from inspiring English sources
Structures of known AA9 proteins are strongly conserved but contain three semi-conserved loop regions, which appear to be relevant for substrate binding.
The experimental structure of Gramicidin GrsA [ 25] bound to its substrate, phenylalanine (1AMU_A), identified a number of residues that may be relevant for substrate specificity.
Key Points Structures of known AA9 proteins are strongly conserved but contain three semi-conserved loop regions, which appear to be relevant for substrate binding.
To confirm that R173 is relevant for substrate recognition, an additional simulation was run of the mutant in the ferric state with 20 chlorite ions randomly placed in the simulation box (cf. simulations OF and RF).
The three-dimensional structure of SMases D from spider venoms consists of a classical 8-barrel with a Mg2+ ion coordinated by the acidic residues (Glu, Asp and Asp), which are relevant for substrate binding, and two catalytic histidine residues, His and His [ 7, 8] (Fig. 9a).
C. albicans itself possesses different types of efflux pumps (Ramage et al., 2002), but as gLuc is located extracellularly, these efflux pumps are unlikely to be relevant for potentially limiting the substrate availability for the bioluminescence reactions in this study.
Our findings are relevant for designing effective substrates for Surface-Enhanced Raman Scattering (SERS) and plasmonic waveguides.
The thermomechanical behavior of metallic thin films on stiff substrates is relevant for thin-film devices, but its mechanisms are not fully understood.
However, it is probable that other RSK phosphorylation targets, both known and undiscovered, are also critical for tumorigenesis, and future work will determine if particular substrates are relevant for specific cancers.
Furthermore, there is a lack of data for adsorption of many metals on substrates that are relevant for natural systems.
C-Jun controls a wide set of substrates that are relevant for cell cycle, proliferation and differentiation [ 19], implying that miR-125b deregulation promotes c-Jun signaling and, therefore, carcinogenesis in malignant melanoma.
