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Hence, proprioceptive acuity seems to be relevant for functional performance.
Taken together, DNAm of C1R does not seem to be relevant for functional changes in AML per se; it rather resembles a biomarker that reflects reorganization of chromatin in a subset of AML patients.
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In addition, the availability of completely sequenced Drosophila genomes representing nine species of the Sophophora subgenus and three species of the Drosophila subgenus [ 19] allowed us to gain novel insight into the molecular evolution and phylogeny of the glob2 and glob3 paralogs, which is relevant for functional interpretations.
Amino acids that are differentially conserved between T2R and V1R receptors, e.g. YT2R/CV1R in EC1, and C..YT2R/S..QV1R in TM3, may be expected to be relevant for the functional differences between T2R and V1R receptors, and would be plausible candidates for a functional analysis by site-directed mutagenesis in future studies.
This may be relevant for neuropsychological as well as for functional neuroimaging studies.
Annotation of the CpG sites that constitute the subtype classifier highlights genes that are known to be relevant for ALL, which suggests a functional role for methylation of these sites but also genes with no known function in ALL are highlighted for further studies.
As we age, functional connectivity in multiple networks may be relevant for understanding variation in cognitive function.
This type of functional interaction could be relevant for the modulation of many yet undiscovered gene targets and contribute to the regulation of p53 transactivation selectivity, tailoring responses to specific cellular stress conditions.
This and other examples of membrane proteins being under positive selection suggests that other proteins in this functional group might be relevant for differences in HIV pathogenesis.
Some other functional features may also be relevant for predicting phosphorylation sites.
The noted long-range effects in single-site mutants are relevant for the functional divergence of closely related galectins and in more general terms, the functionality definition of distinct amino acids.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com