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In conjunction with habitat loss and overfishing, pollution and parasitism are believed to be relevant causes of collapse of Anguilla, as these can affect eel swimming ability and the development of gonads and embryos.
With autoreactivity, intolerance, infection, and other underlying conditions shown to be relevant causes of csU, it is unlikely that IgE-anti-TPO is the relevant mast cell activator in all csU patients.
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13 Nevertheless, tuberculosis and other chronic infections are still relevant causes of AA amyloidosis in other European countries, as well as in developing countries.
Fear of disease progression is known to be a relevant cause of distress in patients with chronic somatic conditions or their partners [ 10].
Both acute myocardial infarctions (AMI) and strokes are known to be a relevant cause of morbidity, mortality, and disability, with their incidence progressively increasing in the oldest age groups.
It can be speculated that this neuronal senescence-like phenotype might be a relevant cause of age-related cognitive dysfunction.
The absence of pathogenic mutations in PINK1 gene in our population is consistent with other studies [ 19, 23, 27], supporting the hypothesis that mutations in PINK1 may not be a relevant cause of EOPD among Brazilian sporadic and familial patients.
Hormonal imbalances, chronic acidosis, and systemic inflammation and oxidative stress are uremia-associated relevant causes of insulin resistance in nonobese individuals.
Especially in the Mediterranean regions the demise of the traditional landscape management practices along the last decades is another relevant cause of wild fires, since large amounts of fuels are accumulated in the forests, increasing the risk of forest fires.
Hypoalbuminaemia is another relevant cause of underdosing in critically ill patients whenever highly protein bound antimicrobials (teicoplanin, ertapenem or ceftriaxone) are used.
Ornamental trees in urban environment are a relevant cause of illness due to allergenic pollen airborne dispersed.
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