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Furthermore, we investigated whether plasma oncomir such as miR-21 could be released from primary oesophageal tumours.
Work by Thompson and colleagues suggests that BDNF may be released from primary sensory nociceptors with activity such as that involved with persistent pain states and inflammatory conditions [ 9].
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However, a question that remains debatable is whether this DNA is released from primary dissociating tumor cells or from cells that invade the blood.
In addition to increased neutrophil numbers in elastase-treated mice infected with RV, we also observed concomitant increased MPO activation, a protein that is released from primary neutrophil granules following activation [ 41].
Although this experimental metastasis assay does not exactly recapitulate pathological metastasis, it has been observed that millions of tumour cells are released from primary tumours yet a few of them actually develop overt metastasis, making this model useful to study the later and perhaps rate-limiting steps of metastasis.
Next, we investigated whether plasma miRNAs could be released from the primary gastric tumours.
Circulating tumour cells (CTCs) can be released from the primary tumour into the blood stream and colonise distant organs giving rise to metastasis.
Therefore, reduction in cellular adhesives may lead to a greater tendency for cells to be released from the primary tumor [ 24].
Cancer cells can be released from a primary site and spread via the bloodstream to form a micrometastatic deposit in distant organs [ 1].
He will never be released from prison.
Through the failure of an important valve to operate correctly, cooling water to the core was lost, parts of the core were melted and the rest of it destroyed, and a large quantity of fission products was released from the primary reactor system to the interior of the containment structure.
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