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In the present study, we used quantitative real-time reverse transcription polymerase chain reaction (qRT-PCR) [ 21] to specifically quantify the CK19 transcript, which is considered to be relatively specific for epithelial cells in the feces of CRC patients.
Dipyridamole, however, an inhibitor that is generally considered to be relatively specific for the cGMP selective PDEs, does inhibit PDE8 with an IC50 of 4.5 microM.
VLA-1 (CD49a+CD29+) expression seems to be relatively specific for lung T cells; only 14% of skin resident T cells, and 48% gut resident T cells, express VLA-1 (Figure 3D).
miR-143/145 are the first miRNAs suggested to be relatively specific for SMCs and play an important role for the regulation of SMC fate and maintenance of the contractile phenotype [6], [11].
To be useful clinically, a sympathomimetic agent would need to be relatively specific for BAT to avoid cardiovascular sequelae.
Although the expression of SSEA5 might be relatively specific for hESCs, other surface markers such as CD9, CD30, CD90 and CD200 are broadly expressed in differentiated tissues.
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Because AT is rarely diagnosed in the acute setting, serology is relatively specific for chronic infection.
Comparison with an independent study of sensitivity profiles for an extensive set of antibiotics pinpoints those effects that are relatively specific for each agent.
Although both TLR7/8 and STING signalling are known to trigger the expression of type I IFN and IFN-γ, STING is expressed ubiquitously in many cell types including epithelial cells, T-lymphocytes, macrophages, and DCs42,44; moreover, the expression of TLR7 is relatively specific for restricted cell populations.
This result indicated that the synthesized PQD-antibody probes are relatively specific for the established targets.
MRI findings are relatively specific for infection, osteoarthritis and fracture, and MRI provides superior evaluation of adjacent soft tissues.
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