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We hypothesized that this set of genes would be regulated through effects on specific transcription factors and, therefore, be suitable for further study aimed at identifying transcriptional control mechanisms downstream from mTORC1.
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The CYP3A4 promoter may also be regulated through mechanisms other than PXR effects, including glucocorticoid-induced CYP3A4 gene expression, through the established PXR-dependent pathway and a PXR-independent pathway [ 99].
These results suggest that increased phosphorylation of CREB protein may contribute to central sensitization following acute peripheral noxious stimuli, and the effect may be regulated through the activation of CaM kinase cascades.
We show that the neuroprotective effects observed are due to its antioxidant effects, caused by induction of pathways known to be regulated through Nrf2/ARE, such as glutathione synthesis.
Moreover, the swelling property of the hydrogel can be regulated through the content of MWCNT-PAA.
The resonance frequency can be regulated through magnetic anisotropy.
Some transcripts may be regulated through the release from repression of PHO2/UBC24 or regulated by other factors such as PHL1.
Hence, PRR5L might be regulated through mTOR phosphorylation.
As mentioned above, EZH2 can be regulated through various mechanisms.
Of special interest is the report by Lumba et al. in BMC Biology on how vegetative transitions are regulated through the effect of the transcription factor FUSCA3 on ethylene-controlled gene expression, providing an elegant example of how hormonal control can be integrated into a developmental pathway.
This emphasizes the point that LIF effects are regulated through the synthesis of repressors (e.g., Socs3).
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