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In conclusion, myocardial tissue grafts engineered with cell sheet technology have their own inherent potential for the in vivo neovascularization that can be regulated in vitro.
The lipL41, ligA and sph2 genes are known to be regulated in vitro by physiological conditions [44], [46], [47], [48].
Alternative TSS usage in colorectal adenoma and cancer samples has been shown for nine genes, and OSBPL1A and TRAK1 were found to be regulated in vitro by Wnt signaling.
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The HFEA has been regulating in-vitro fertilisation and research on human embryos and human embryonic stem cells in the UK since 1990.
How PD-1 is regulated in vitro is unclear.
To elucidate processes explaining how antler growth is regulated, in vitro cultures have been established.
Furthermore, the expression of zona occludens 1 (TJP1) in rats is regulated in vitro during the assembly of inter-Sertoli tight junctions during spermatogenesis [ 33] while JAM-3 is a protein required for spermatid differentiation [ 34].
The suggestion that a set of genes associated with hormone independence in breast cancer were regulated in vivo but not in vitro seemed intriguing but was not further explored in this study.
The differences in the response to bacterial challenge of mammary epithelial cells in vivo and in vitro have been partially characterized by [ 8, 45], indicating that only a subset of the genes involved in the immune response in vivo are regulated in mammary epithelial cells in vitro and that there is a difference in the time-course of the response.
Additionally, the activity of the migration/invasion regulator Rac, which we have previously shown to be regulated by resveratrol in vitro, was measured in tumors from resveratrol treated mice.
The ability of RA to promote neurogenesis and improve memory abilities in VAD rats could be in part mediated by activation of neurogenesis-related gene expression via neurotrophin receptors, which are known to be regulated by RA in vitro [30], [42] [46].
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