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SATB1 is a genome organizer protein that facilitates these processes, providing a nuclear architectural platform that anchors hundreds of genes, through its interaction with specific genomic sequences; this activity allows expression of all these genes to be regulated in parallel, and enables cells to thereby alter their function.
Because DNA catenations persist without PIASγ in the absence of cohesin, removal of catenations and cohesin rings must be regulated in parallel.
However the approach adopted here can be justified at least in part by the fact that both SOD2 and catalase seem to be regulated in parallel by FOXO [ 54, 83].
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It also provides broad and useful information to explore potential two-way level of gene expression control regulation in which microRNAs target multiple mRNAs, and, target mRNAs are regulated in parallel by multiple microRNAs.
Amongst them were the complex I subunits Ndufb2 and Ndufs2, which were regulated in parallel with genes for synaptic function, signal transduction and ion channels [36].
We have previously shown that the processes of DNL and desaturation are regulated in parallel (10).
Most transcripts were either significantly regulated for one or the other gill, only 11% were regulated in parallel.
MCIP expression as an indicator of calcineurin activity was regulated in parallel to SERCA after 6 and 24 h.
The selection of putative causative genes may consider groups of genes that are regulated in parallel and are members of the same metabolic pathway.
A detailed comparison reveals that only a small number of commonly regulated genes may be identified in the datasets that are regulated in parallel or opposite direction.
GSC absence results in activation of transcription factors in the intestine, with SKN-1 being regulated in parallel to DAF-12 and DAF-16.
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