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Exact(15)
Such cavities are uncommon except in the case of ligand-binding proteins, leading to the hypothesis that HIF-2α can be regulated by small molecules.
The pyruvate kinase activity of PKM2 could be regulated by small molecules.
It is not known whether hormone synthesis in eukaryotic cells could also be regulated by small molecules acting through riboswitches.
These are engineered nucleic acid whose activity can be regulated by small molecules or cofactors.
According to our data the mitochondrial motility can be regulated by small GTPases of Rho family (Minin et al., 2006).
For example, it is possible that, like in many other metabolic enzymes, hGALE's activity can be regulated by small molecule effectors.
Similar(45)
They can also either encode or be regulated by smaller ncRNAs, such as miRNAs.
This is perhaps the first example of RNA binding protein regulation by a small molecule ligand, similar to the many examples of transcriptional regulators, such as the nuclear hormone receptors, that are regulated by small ligands.
More typically, the activity of OCS sensory domains is regulated by small molecule binding, for instance the PurR regulator acts as repressor of purine biosynthesis upon binding a purine co-repressor [ 4].
COPI coat assembly is regulated by small GTPases of the Arf family and their regulator, the GTP exchange factor, GBF1; however, the regulation of COPI-coated carrier formation in response to extracellular signals is poorly understood.
These events are regulated by small Rab GTPases.
More suggestions(17)
be regulated by low
be restricted by small
be regulated by posttranslational
be regulated by external
be regulated by multiple
be controlled by small
be regulated by transcriptional
be regulated by neural
be explained by small
be regulated by different
be regulated by other
be regulated by environmental
be caused by small
be regulated by additional
be regulated by many
be regulated by active
be regulated by common
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