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Interestingly, transcription from the spa promoter was suggested to be regulated by negative (SarA) and positive regulators (SarS and Rot) competing for overlapping operator sites [13].
These results indicate that At1g78240 mRNA expression could be regulated by negative feedback.
The differentiation process in MCF-7 cells could therefore be regulated by negative feedback control from the transcriptional network.
Signaling pathways are known to be regulated by negative feedback loops that limit intracellular responses upon sustained stimulation.
Several studies have shown that organ size, and the proliferation of tumor metastases, may be regulated by negative feedback loops in which autocrine secreted factors called chalones inhibit proliferation.
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IL-6 signaling systems are regulated by negative feedback by the suppressors of cytokine signaling (SOCS) and the protein inhibitors of activated STATs (PIAS).
Synthesis of milk by the secretory epithelial cells is regulated by negative feedback, as the lumen becomes filled with milk and prevents overfilling.
It is thus important to evaluate the evidence that granulocyte production is regulated by negative feedback and the prospects that granulocyte excess (cell inflation) would reduce progenitor division rate.
Effects are regulated by negative feedback involving the inhibitory neurohormone, somatostatin, so that unlike administration of exogenous rhGH, overdoses of endogenous hGH are difficult if not impossible to achieve, Because of the interactive effects of sermorelin and somatostain, release of hGH by the pituitary is episodic or intermittent rather than constant as with injected rhGH.
Earth's temperature is thought to be regulated by a negative feedback between atmospheric CO2 levels and chemical weathering of silicate rocks that operates over million-year time scales.
These types of enhancers could be regulated by a negative feedback mechanism: an increase in transcription leads to a decrease in enhancer activity, thereby preventing excessive activation of the target gene.
More suggestions(15)
be caused by negative
be hijacked by negative
be affected by negative
be regulated by relevant
be generated by negative
be hit by negative
be targeted by negative
be buffeted by negative
be limited by negative
be offset by negative
be regulated by retail
be distracted by negative
be bombarded by negative
be hurt by negative
be toppled by negative
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