Sentence examples for be regulated by binding from inspiring English sources

In addition to the regulation of gene transcription, initiation of DNA replication has been proposed to be regulated by binding of replication machinery to the nuclear scaffold/matrix [20], [46].

TTP activity is also thought to be regulated by binding proteins, including Ccr4, Dcp, Xrn1 [48], MK2 [31], 14-3-3 [49], RISC components Ago/eiF2C [50], nuclear pore protein Nup214 [51] and PP2A [33].

However, experimental and computational criteria suggest that most genes whose expression is affected by the Leu3 genotype are unlikely to be regulated by binding of the protein.

Release of these growth factors is possible but appears to be regulated by binding of integrins to extracellular matrix components and other factors such as oestrogen stimulation (Mousa et al, 1999).

Active CDK/cyclin complex can be regulated by binding to CDKI (p16 INK 4 A, p21 waf 1 and p27 KIP 1) and inhibit cell cycle progression from G1 to S phase [ 7].

Studies in mammalian eggs suggest that the release of cortical granules in mature eggs is dependent upon calcium-dependent synaptosome-associated protein 25 (SNAP-25) which might be regulated by binding to Ca2+-dependent synaptotagmins as it occurs in neurons [ 56, 57].

Beyond regulation of proteolytic activities by alternative incorporation of catalytic subunits, protein degradation by the proteasome is regulated by binding of proteasomal regulators to the catalytic 20S core particle.

In mammalian cells, cell cycle progression is governed by distinct cyclin-dependent kinases (cdks) whose activities are regulated by binding of their activating cyclin subunits and through negative regulation by inhibitor proteins such as p21.

For nuclear estrogen receptor mediated effects via regulation of gene activity (nuclear estrogen receptors are transcription factors whose activity is regulated by binding to estrogen), prior studies have typically shown a 1,000-fold 1,000-foldvity for BPA relowere to estractivity potent estrogenic drugs, including DES and ethinylestradiol.

Similarly to vertebrate IGFs, the bioavailability and bioactivity of CRFs is regulated by binding proteins.

p53 is the major tumour suppressor in humans and is regulated by binding to hDM2.