Sentence examples for be regulated by alterations from inspiring English sources
These findings emphasize that miR-mediated repression could be regulated by alterations in the biogenesis as well as the activity of RISC-associated miRNA.
It is conceivable that such antagonism may be regulated by alterations in the relative expression of the cofactors, posttranslational modifications (Christian et al., 2006; Gerhart-Hines et al., 2007), or their subcellular localization (Lerin et al., 2006).
Transcriptional activation is regulated by alterations to the chromatin template.
Cell proliferation, migration and cell death are regulated by alterations of cytosolic Ca2+ activity [ 20– 23].
Many different aspects of neuronal function, including neurotransmitter release from synaptic vesicles, are regulated by alterations in the concentration of intracellular free Ca2+ [ 1, 2].
Recently, we determined that both expression and function of MBP-1 are regulated by alterations in exogenous glucose concentrations and correspond to changes in cell proliferation and lactate production [ 26].
The only exceptions to this are the trypanosome VSG and procyclin transcription units, which are still polycistronic, but are transcribed by RNA polymerase I [ 16]; their transcription is regulated by alterations in chromatin [ 17] but the mRNAs are also still subject to extensive post-transcriptional control [ 13, 14].
MiRNAs can, therefore, alter the epigenetic machinery and also be regulated by epigenetic alterations.
They also showed that uc.283-minus undergoes specific CpG island hypermethylation, suggesting that it could be regulated by epigenetic alteration.
This suggests that spontaneously occurring transcriptome alterations, which may be regulated by epigenetic mechanisms similar to the serotype system, alter gene expression in Paramecium to a much higher degree compared with short-time adaptation to environmental changes.
(7, 8) Tumorigenesis in the bladder is a multistep process that is believed to be regulated by several aberrantly expressed genes that cause alterations of morphological and molecular features.
