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The involvement of inflammation in melanoma, the most malignant type of skin cancer, is indicated by the upregulation of inflammatory cytokines including IL-6, IL-8, CCL5, and IL-1β, all of which can be regulated by active IL-1β (Raman et al., 2007; Dinarello, 2009).
Note that in living cells clustering may in part be regulated by active, energy-dependent mechanisms.
In vivo AMDV-G infection might thus be regulated by active caspases because it only occurs at 37 °C.
The cytoplasmic free calcium gradient connected to apical invasive growth seems to be regulated by active Rop GTPases via Ric proteins [ 100].
However, a novel feature of this study is provided from data indicating that apoptosis can be regulated by active DNA demethylation, thus revealing a new approach for the understanding of cell death regulation.
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The availability of β-catenin is regulated by active glycogen synthase kinase 3β (GSK-3β), which in turn is inactivated by phosphorylated ERK.
With these experimental settings, we were able to further confirm our hypothesis that the expression of the LAA PR-3, RHAMM and Survivin is regulated by active FLT3.
Apart from the transcription factors that are regulated by active ERK 1/2 (e.g., c-fos, ets), a number of apoptosis-related proteins, such as Bad, are also directly affected.
The activation of the Wnt/β-catenin pathway in our model of ATII-to-ATI cell trans-differentiation prompted us to evaluate if the newly identified proteins are regulated by active β-catenin signaling.
Given that the gradient of free Ca2+ in the cytosol dissipates within 1-2 seconds [ 36], it appears more likely that cilia form their own compartment where Ca2+ is regulated by active Ca2+ transport in a similar fashion to the intracellular Ca2+ regulatory system.
It is worth noting that nuclear localization of active caspase-3 appears to be regulated by an active transport system.
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be transferred by active
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