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Also, microtubule flux can be regulated both by minus and plus ends of microtubules in the spindle.
Indeed the expression of some genes, including ADAM28, DNASEIL3, and CCL2, appeared to be regulated both by TNF and platelets, and the expression of other genes (GPR83, IER3, RAB4, and HLA-DRB1) was altered by an interaction between TNF and PL.
These proteins have been shown to be regulated both by ABA and water stress [ 57].
Thus, a specific lipid composition at the midbody might be regulated both by specific trafficking and by local synthesis.
The binding of the dual-specificity protein phosphatase SEX4 (DSP4, At3g52180) has been shown, in vitro to be regulated both by pH and redox potential [ 7].
The functions of Tau may be regulated both by alternative splicing (six isoforms are expressed in the human CNS) and through a multitude of post-translational modifications.
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Moreover, the PA induced autophagy was regulated both by ACC2 suppression and CPTI inhibitor treatment, which represent an altered fatty acid β-oxidation.
Altogether our findings indicate that the activity of the vATPase in the endocytic pathway is regulated both by reversible association/dissociation and the interaction with specific lipid environments.
LFA-1 activity is regulated both by an upregulation of affinity for its ligand and clustering at the immune synapse following TCR stimulation (reviewed in [3]).
Pol II-dependent RP and RIBI gene transcription is regulated both by repression and by activation.
Cofilin phosphorylation is regulated both by kinases (LIMK family) and phosphatases (SSH family).
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Justyna Jupowicz-Kozak
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