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Wnt/ β-catenin signaling can be regulated at multiple steps (for example, regulation of β-catenin protein levels, β-catenin nuclear localization, β-catenin/TCF interaction, or interactions between β-catenin and transcriptional mediator proteins).
Nitric oxide synthase gene expression may be regulated at multiple levels: epigenetic, transcriptional, and posttranscriptional processes [26].
Apoptosis is a complex process that proceeds through at least two main pathways (extrinsic and intrinsic), each of which can be regulated at multiple levels.
For example, gene expression can be regulated at multiple levels that include epigenetic modulation by DNA methylation or through histone modifications that modify chromatin accessibility.
Protein synthesis is known to be regulated at multiple levels in response to different signals and various types of cellular stress.
miRNA expression may be regulated at multiple steps of RNA biogenesis [50].
Similar(34)
The second level to look for RNA-centric regulation is gene-cluster organization that is regulated at multiple levels, such as organization of chromosomal elements or sequence repeats, nucleosome positioning, histone marks, antisense RNAs and transcriptional regulation [29 33].
It seems certain that, in addition to miRNA regulation, the production and secretion of hPGRN is regulated at multiple levels by several other mechanisms.
Metastasis formation requires active energy production and is regulated at multiple levels by mitochondrial metabolism.
Plant terpene biosynthesis is regulated at multiple levels, leading to wide variability in terpene content and chemistry.
Recent studies have shown that alkaloid pathways are regulated at multiple levels, including cell type-specific gene expression, induction by light and elicitors, enzymatic controls, and other poorly understood metabolic mechanisms.
More suggestions(15)
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be regulated at transcriptional
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