Except for chance, visits to a web site can be regarded as affected by the intrinsic appeal of the particular site to web users (corresponding to proneness) as well as by exogenous factors (corresponding to external factors) such as, links provided by other sites to the particular site, how well the site is advertised etc. Letting ν denote the intrinsic factors and λ|ν the exogenous factors.
Namely, those links with more than 20% positive or negative flow change are regarded as affected links.
Individuals were regarded as affected if typical corneal features of SCCD were present on slit lamp examination, or in documentary slit lamp images, or if corneal transplantation had been performed with SCCD as the underlying diagnosis.
Furthermore, 12 loci (AGLA29, BMS2361, BM2113, ETH10, ETH225, CSSM66, ETH152, HAUT24, CSRM60, BMS2461, HEL5 and DIK4591) can be regarded as candidates affected by selection, but were revealed only in one of the three tests.
Taken together, our results indicate that patients with early SSc or UCTD in whom a scleroderma-like functional internal organ involvement has been detected should be regarded as being affected by SSc and, therefore, challenge the time-honoured practice of calculating the duration of SSc starting from the first non-RP symptom.
These may be regarded as unusual features affecting the generalisablity of our findings but we have argued in our introduction that 'unusual' (ie, not clinical intervention) reviews are becoming more common and hence are an emerging priority in terms of review methods.
The rationale is that the model without LOS should be a "pure" prediction model since LOS can be regarded as an outcome affected by patient characteristics and hospital care quality.
