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be refractory
adjective
Obstinate and unruly; strongly opposed to something.
Exact(60)
Chronic vulvovaginal pruritus can be refractory to standard treatment.
Therefore, the dust must be refractory to condense, and abundant to be detected by observations.
In contrast, Gcn5-dependent H3K36 acetylation may be refractory to Ku recruitment and could instead function to recruit HR factors.
Some patients with chronic extensive alopecia areata (AA) may be refractory to topical immunotherapy.
Approximately 10% of benign esophageal strictures appear to be refractory to standard dilation therapy.
Furthermore, patients may be refractory or may become resistant to tamoxifen treatment.
We have determined the sequence of CD81 from the tamarin, a primate species known to be refractory to HCV infection.
All the silicides investigated were found to be refractory, hard, metallic materials and no magnetism was found in the ground state structures.
As both start codon stringency and initiation kinetics are modulated in response to eIF2α phosphorylation following ISR activation30, 31, 33, 41, we hypothesized that RAN translation might be refractory to ISR-activation.
Together these studies suggest that zinc deficiency leads to the development of depression-like behaviors that may be refractory to antidepressant treatment.
Anti-VEGF biologics are the standard of care, but may cause ocular or systemic side effects after intraocular administration and patients may be refractory.
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