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Bone metabolism can be reflected by bone turnover markers (BTM).
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Our PET-CT data suggest that AS activity is reflected by bone activity (formation) rather than inflammation.
Despite the limited number of patients investigated in this study, our PET-CT results suggest that AS activity was reflected by bone formation and not by inflammation, and this finding throws an interesting light on the pathogenesis of the disease.
Conversely if a less robust skeletal phenotype were to be due to a lower osteogenic responsiveness to loading this should be reflected by a lower level of bone loss associated with disuse.
Inter-group differences at diagnosis and changes in Wnt signaling following off-loading treatment were sufficiently large to be reflected by systemic levels, indicating that this pathway has a role in bone remodeling and bone repair activity in Charcot patients.
This may be reflected by their tumorigenicity.
In long-standing AS, reduced bone mass is reflected by low bone mineral density (BMD), particularly in the hips.
The sonographic signal is reflected by cortical bone [ 6], and any metallic implant has a hyperechoic image.
Bisphosphonates, including zoledronic acid, exert their skeletal effects through inhibition of osteoclastic bone resorption, which is reflected by a decrease in bone resorption markers.
This concept is reflected by the fact that bone erosion is part of the diagnostic criteria of RA and has become a valuable tool for monitoring the disease [ 30- 34].
The higher sensitivity of NaF PET/CT compared to bone scan was reflected by higher manual PET index than BSI being more common than the opposite finding, and a slightly but not significantly higher C-index.
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