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Exact(9)
CGH in principle defines only the chromosomal structural changes, but the functional effects of CNAs can be reflected by altered gene expression.
In addition, the CNAs identified by GEP would be more functionally relevant CNAs in the disease pathogenesis since the functional effects of CNAs can be reflected by altered gene expression.
These nontranscriptional alterations in protein stability would be reflected by altered steady-state concentrations of proteins whose expression is not affected by stress-independent HSF1 activation.
A shift in VDA indicates a change in the relative free energy (ΔG) of the closed and open states of the channel, versus a change in the activation energy (or transition-state energy barrier, ΔEa), which would be reflected by altered activation kinetics.
Thus, mitochondrial dysfunction in AD cells may be reflected by altered dNTP ratios (i.e. imbalance in dNTP pools).
It has been fairly well confirmed that the propensity of many diseases can be reflected by altered gene and protein expression levels in particular cell types [ 3, 4].
Similar(51)
In addition to altering starch accumulation this could also be reflected by a change in soluble sugar levels [ 25, 26].
This potential niche expansion may be reflected by higher microbial diversity in the more altered rocks.
Hence, changes in reaction conditions or the structures that alter Keq must be reflected by corresponding changes in BA k and/or AB k.
This may be reflected by their tumorigenicity.
Intriguingly, tumour-derived mutant p53 usually not only lost wild-type activities but frequently enhances cell proliferation and invasiveness, which is reflected by an altered p53-dependent transcriptional program.
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