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The technique of sentinel node biopsy may avoid axillary dissection in 85 90% of patients without lymph node involvement (level of evidence: B1), but cannot be recommended until the results of ongoing studies are available (recommendation, expert agreement).
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Although, results obtained from this interim analysis are encouraging, caution is recommended until the results obtained show statistical difference in pCR.
In this targeted population, as well as for the general population, exclusive breastfeeding is recommended until the age of 6 months.
Following 3 d of pretreatment, FK506 immunosuppression (1 mg/ kg·d)) is recommended until the nerve growth has crossed the distal graft site [ 3].
A strict nonweight bearing protocol was recommended until the radiographs showed early callus mineralization (stage 1), after which partial weight bearing was allowed and gradually increased.
This concept, which has also been described by Hoste et al. in a slightly modified version, focuses on the clinical phases of shock from the initial "Salvage" or "Rescue" phase (where maintenance of a life-saving blood pressure with bolus infusion of fluids is recommended) until the "De-Escalation" phase (where a negative fluid balance should be achieved) [ 18, 19].
Despite these promising data, however, the recent American Society of Oncology guidelines have stated that even the use of the US Food and Drug Administration-cleared CellSeassayassay in patients with metastatic breast cancer cannot be recommended until further validation confirms the clinical value of this test [ 72].
So caution is recommended until this premium comes down to the historical average in the low single digits.
IIF is a bit pricey right now and trades at a 14% premium to net asset value, so caution is recommended until this premium comes down to the historical average in the low single digits.
The use of the MMP for prostate cancer patients at this stage of evaluation cannot be recommended until prospective randomised control trials to compare the utility of the MMP with good clinical practice have been completed.
Despite the promising findings of this most recent work, the routine peri-operative use of ScvO2-guided GDT cannot be recommended until a large randomised trial has confirmed the value of this approach.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com