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First, the most likely reason for this differential pattern is that certain B. p antigens may be recognized differently by the murine and human host immune systems, which contributes to the observed differences.
Finally, motifs may be recognized differently by DNA repair mechanisms (see Harr and Schlötterer 2000; Schlötterer et al., 2006).
We speculated that tripeptides would therefore be recognized differently, with important implications for understanding the transport of β-lactam antibiotics, which are similar to tripeptides in size (Supplementary Fig S6).
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Different forms of hormones are recognized differently by cells, so it makes sense that their effects might also be different.
If antiestrogens are recognized differently by the cell as it has been suggested, then in disease conditions where tamoxifen fails to function effectively, a mechanistically different antiestrogen might yield successful results.
How should loyalty from the best and/or most valuable customers be recognized and rewarded differently from that of typical or average customers?
Transcription of AAT repeats and ATT repeats may produce distinct repeats DNA conformations that may differently be recognized by H-NS, and therefore differently affect the IS1E transpositions.
Finally, the fact that the GPI-T signal sequence lacks a consensus sequence but appears to be recognized by various GPI-T orthologues differently raises the possibility that structural variations could participate in dictating sequence specificity.
Adjuvant chemotherapy could be recognized as one possible confounding factor, because it has been postulated that basal-like and non-basal tumors would respond differently to chemotherapy [ 39].
The mutations we have analysed here affect differently these regulatory elements and probably block splicing at the first step when the exon has to be recognized co-transcriptionally.
Bjerke [ 54], in a study of children's view of agency in child-adult relation within home and school contexts, argued "that children not necessarily ask for increased independence from adults, but rather to be recognized as 'differently equal' partners in shared decision-making processes, where children are being treated with dignity and respect as valuable persons" (p.93).
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com