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Contrary to gut and oral cavity, skin-enriched cluster could be recognized by four clustering criterions in all experimental settings, inferring skin samples have many cluster patterns with diverse microbial structures.
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Of note, the epitope "TTPWTYFNFNQY" was found to be recognized by fifteen different alleles belonging to seven HLA supertypes (A1, A3, A24, A26, B7, B58 and B62).
"It is a funding issue and also a way to be recognized by one's peers".
Although our study demonstrated BP3 could bind and activate γδ T cells, we had not yet determined whether its matched protein could be recognized by γδ T cells.
Finally, recent studies have shown that LIN-28 may recognize the pre-let-7 loop nucleotides and block the processing of human pri-let-7 RNAs into mature miRNAs in embryonic stem cells, suggesting that pre-miRNA loops may be recognized by LIN-28 or LIN-28-like RNA binding factors that control mature miRNA biogenesis [23] [25].
In some cases, one mimic site might be recognized by two or more different miRNAs (especially for the members of the same miRNA families).
Thus, it is possible that a single paratope can bind two unrelated peptides (mimitopes), or a particular epitope can be recognized by two different paratopes with no sequence similarity.
It was shown recently that cytoplasmic dsDNA could be recognized by two cytosolic dsDNA sensors: DNA-dependent activator of interferon regulatory factors (IRFs), and absent in melanoma 2 - both signal through TBK1 and IRF3, and induce genes for IFNβ and proinflammatory cytokines [ 56].
A butterfly bandage can be recognized by two sticky adhesive strips connected by a thin, non-sticky strip of bandage.
Her outstanding teaching at Rice was recognized by four university-wide teaching awards.
Discoveries here have been recognized by six Nobel prizes.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com