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At first these primer sequences, either fully preserved or just fragments, have to be recognized and removed.
Misfolded proteins must be recognized and removed, which is achieved by their targeting for ER associated protein degradation (ERAD) and subsequent retrotranslocation to cytosol [ 123].
Neutrophils from SLE patients have a reduced ability to be recognized and removed by the C1q/calreticulin/CD91-mediated apoptotic pathway, despite the presence of main apoptotic recognition partners [ 58].
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Muscle contractile proteins are expressed as a series of developmental isoforms that are in constant dynamic remodeling during embryogenesis, but how obsolete molecules are recognized and removed is not known.
The artifact components were recognized and removed by sorting the correlation of the marked a priori artifact information and WICs.
The N-methylpurines noted above are recognized and removed from DNA by N-methylpurine-DNA glycosylaliasMPG, alias N-alkylpurine-DNA glycosylase, Aag).
Melphalan-induced alkylated bases are recognized and removed by particular glycosylases such as methylpurine glycosylase (MPG) leaving an abasic site with the N-glycosyl bond intact.
Oxidative stress can produce DNA lesions such as 8-oxoguanine (8-OxoG), which are recognized and removed by cellular DNA glycosylases leaving abasic sites.
However, how these misfolded proteins are recognized and removed by the autophagy pathway is unclear [ 99] though unfolded protein response (UPR) pathway, JNK pathway, and PERK pathway have been reported to be involved in that [ 100– 100].
Ubiquitinated PEX5 is recognized and removed from the peroxisomal membrane by a complex of the PEX1 and PEX6 ATPases [ 17– 19] and PEX26, which recruits the PEX1-PEX6 hetorohexamer thethe peroxisome [ 19– 219.
Similar to HAC1 mRNA splicing in S. cerevisiae, the mRNA encoding for the mammalian transcription factor XBP1 retains a short, 26-nucleotide intron after canonical splicing, which is recognized and removed by activated IRE1 (Yoshida et al, 2001).
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CEO of Professional Science Editing for Scientists @ prosciediting.com