An accident, also known as an unintentional injury, is an undesirable, incidental, and unplanned event that could have been prevented had circumstances leading up to the accident been recognized, and acted upon, prior to its occurrence [3].
It must be promptly recognized and acted upon, or it will go on and on and get worse and worse.
They have no known catalytic function - they are just 22 or so nucleotides that target another RNA, and the resulting complex, in some fashion that's not fully understood, is then recognized and acted upon by a generic protein complex, the so-called RISC complex.
An antimetabolite is similar in structure to a metabolite, or enzymatic substrate, which is normally recognized and acted upon by an enzyme to form a substance required by the cell.
Whether the crisis is set in motion intentionally, or rises from other conditions, it creates an opportunity that can be successfully exploited if recognized and acted upon — or not acted upon.
The completion of the ATPase cycle may render cohesin in a conformation capable of being recognized by and acted upon Wpl1, which leads to cohesin dissociation from DNA.
It is also possible that patients in the most deprived areas were inherently more prone to adverse events due to greater comorbidity, and perhaps were slower to recognize and act upon the development of an adverse event before it became serious enough for emergency readmission, but we are not aware of any data to support this hypothesis.
