Sentence examples for be recapitulated in models from inspiring English sources

That said, however, neither the complexity nor the variability or randomness that occurs in nature occurs or can be recapitulated in models systems.

In summary, these proof-of-principle studies suggest it will be important to determine if the in vitro efficacy of KU-32 in decreasing demyelination can be recapitulated in models of chemical-induced demyelinating neuropathy or a rodent model of DPN that superimposes diabetes on genetically hypertensive rats to enhance myelin thinning (Gregory et al., 2012).

These properties should be recapitulated in computational models of the circadian clock.

Important to synucleinopathies, activation of the UPR seems to be an early event in the pathogenesis of PD [ 153, 154] and MSA [ 155], a finding that can be recapitulated in diseases models in vitro and in vivo[ 156– 156].

These changes can be recapitulated in mouse models of DNL, with the caveat that humans appear to produce a wider range of TAGs in terms of both fatty acid chain length and degree of unsaturation.

To clarify whether these intriguing adverse effects of genistein are intrinsic to the orthotopic prostate tumor model, or these results could also be recapitulated in another model, we used the orthotopic metastatic KCI-18 renal cell carcinoma (RCC) model established in our laboratory.

Furthermore, the findings reviewed here must be recapitulated in other experimental models, extended from in vitro to in vivo models, and ultimately appraised in the context of human biology.

Here we have shown that these defects in glutamatergic signaling can be recapitulated in the fly models for both syndromes as well, validating the fly model system for both syndromes.

Importantly, the CR-associated SIRT1 increases observed in animals can be recapitulated in in vitro models of CR.

This pathogenic time course can be recapitulated in experimental animal models of TLE, although specific disease mechanisms remain poorly understood.

Previous reports showed that growth of human tumours could be recapitulated in non-murine models such as the zebrafish.