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implications if this process could be recapitulated in human cells.
We therefore assessed whether our in vitro results might be recapitulated in in vivo mouse models.
Musculoskeletal tissues possess extensive vasculature, which should be recapitulated in tissue-engineering approaches.
We demonstrate that the entire HCV life-cycle can be recapitulated in mouse cells.
Angiogenesis is a multistep process that encompasses complex molecular and cellular interactions that can not be recapitulated in vitro.
Endocardial and myocardial lineages are segregated early during embryogenesis and such a cell fate decision can be recapitulated in vitro by embryonic stem cells (ESC).
Our experiments investigated whether these changes in dendritic morphology could be recapitulated in a genetic model of NMDAR hypofunction, the serine racemase knockout (SR−/−) mouse.
In this perspective, the flourishing interest in hydrogels as cellular substrates has highlighted the main parameters directing cell differentiation that need to be recapitulated in artificial matrix.
This behavioral effect could not be recapitulated in mice with reduced BDNF expression (Saarelainen et al. 2003), suggesting that BDNF signaling is necessary for the antidepressant effect.
These properties should be recapitulated in computational models of the circadian clock.
The enhanced apoptosis caused by diclofenac in vivo could not be recapitulated in vitro.
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CEO of Professional Science Editing for Scientists @ prosciediting.com