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We determined that the IL-6−/− phenotype could be recapitulated by blocking IL-6 signaling using a neutralizing IL-6 mAb.
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If a large-scale abnormality in translational repression prevented meiotic maturation, one might imagine that such a block might be recapitulated by other mutations that perturb gene expression in oocytes or other insults to oocyte physiology.
We propose that angiogenic events leading to vascularization can be recapitulated by harnessing the inflammatory responses.
Importantly, this particular phenotype could be recapitulated by stimulating monocytes with IFN-α [20].
Better chemotactic ability, which could be recapitulated by the above-mentioned parameters, confers evolution advantage.
Predictions made by this model could be recapitulated by iAB-RBC-283.
This effect could be recapitulated by siRNA-mediated knock-down of HDAC1 but not HDAC2.
Resetting of telomere length can be recapitulated by nuclear cloning using terminally differentiated cells.
In vitro studies suggest that its chromatin remodeling properties can be recapitulated by recombinant BRG1.
This migration phenotype could be recapitulated by employing early passage cIAP1−/− as well as XIAP−/− MEFs.
This phenotype is specific because it can be recapitulated by secondary RNAi lines and in integrin mutants.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com