We propose that angiogenic events leading to vascularization can be recapitulated by harnessing the inflammatory responses.
Better chemotactic ability, which could be recapitulated by the above-mentioned parameters, confers evolution advantage.
Importantly, this particular phenotype could be recapitulated by stimulating monocytes with IFN-α [20].
From these experiments it is concluded that the salubrinal-mediated increase in PSI toxicity could be recapitulated by a second phosphatase inhibitor that supposedly targets PP1.
Therefore, the fiber type-specific muscle atrophic response appears to be relevant to various cachectic conditions that can be recapitulated by endotoxin injection.
We determined that the IL-6−/− phenotype could be recapitulated by blocking IL-6 signaling using a neutralizing IL-6 mAb.
The output from the naturally very dynamic CLN2 gene can be recapitulated by maximal induction of MET3pr for 15 minutes, with a cell-cell variability of about 25%.
This process can be recapitulated by culture on air-liquid interface (ALI), where undifferentiated basal cells differentiate into ciliated and secretory cells [9] [14].
To confirm binding between Dsh and this putative partial-length Hipk clone, we tested whether an interaction could be recapitulated by in vitro pull-down assay.
We found that the effects of N2 and B27 could only partially be recapitulated by insulin alone (INS) (Fig. 4h), suggesting that additional factors are responsible for the net effects of N2 and B27 (Fig. 4f).
Alternatively, some of these genes may only be regulated in vivo, a condition that cannot be recapitulated by in vitro cell culture model, even though the GR binding phenotype is conserved in 3T3-L1 adipocytes.
