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I hate to be reasonable at this historic moment, but the principle of Occam's razor favors the lesser idiot theory.And so the quotation and the fund-raiser don't really feed the case for conspiracy.
Whilst such a strategy would normally be performed once a selective and relatively potent inhibitor had been found, we postulated that it would be reasonable at this early stage of inhibitor design to attempt this in order to establish if ligand inhibition was at all possible before addressing selectivity in later rounds of ligand optimisation.
However, it may be reasonable at this juncture to consider changing to a stronger medication or to a medication that has a different route of administration.
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The Supreme Court has held that to satisfy the Fourth Amendment, a search of a student by school officials must be reasonable at the start.
"But the investment only has to be reasonable at the moment it is made-not next week or next year.
American environmental rules are serious, but environmental regulators know that they have to be "reasonable" at the same time.
"No question some of our people in the Republican conference would like to have 65 votes and don't like this, but the overwhelming majority of our conference felt this was reasonable at this time," Mr. Lott said.
A deviation of 0.5 to 2 Da is reasonable at this high mass range.
Although there are no large randomized studies focused on MV settings during ECMO in severe acute respiratory failure, it is reasonable, at this time, to advise an ultra-protective ventilation strategy with ECMO, based on a tidal volume reduction (that is, <4 ml/kg PBW) and on a plateau pressure reduction (that is, ≤25 cmH2O), provided lung recruitment with PEEP is sufficient.
Nonetheless, the use of self-reported stressors through a reliable and valid questionnaire is reasonable at this stage of investigation, as some research suggests that information derived from self-report checklists of stressors is comparable to information and associations obtained from life event interviews (Lewinsohn et al. 2003; Wagner et al. 2006).
I don't think this would be reasonable (at least by today's standards—I'll leave it to Gorsuch to divine ancient tribal understandings here).
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com