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However, it has to be realized that, although we detect the statistical excess of non-synonymous over synonymous substitutions, the tests describe here, by themselves, do not allow us to assign an individual substitution to the gain-of-function or loss of function category.
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Therefore, a community analysis of a given network can provide a first indication as to whether it is going to exhibit coordination failures or not, although it must be realized that communities themselves may contain inner topological traps which could prevent them from coordinating in a unique equilibrium (as seen also in [34]).
In other words, I'm realizing that although they are often used interchangeably, there may be a very important difference between the terms happiness and joy.
They're realizing that although we may live miles apart and in different realities, those differences are real and we're in this nation together.
And I'm realizing that although my kids' holidays might involved inconsistent stockings and manger scenes, one thing is consistent -- my ability to keep it interesting.
The inter-story drift is used as an effective response variable to define fragilities and failure costs, although it is realized that damage of some components may be better expressed in terms of the acceleration response.
Although, it was realized that self-report of weight may not be the most accurate method this way was considered most practical [ 16, 17].
Although it has been realized that a close phylogenetic relationship exists, so far sharp distinction has been made between the obligate biotrophic downy mildews and the hemibiotrophic Phytophthora.
Thus, scientists have been interested in studying the relationship between morphology and chondrocyte behavior in vitro using monolayer cultures to induce dedifferentiation, although it has been realized that the monolayer expansion of chondrocytes can alter the differentiated phenotype [ 64].
I realized that although mom friends are super important, I would not have survived these past 4 years without my special aunties and uncles.
It should be realized, however, that although controlling for childhood BMI and TSF greatly reduced the inverse relation of menarcheal age to adult obesity, a relatively small, independent association remained.
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