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This technology allows high-affinity peptidic macrocycles containing modified backbones and unnatural side chains to be readily selected based on target binding.
The lethality and locomotion defects were maternally rescued; double-homozygous mutant F2 progeny from a double-heterozygote parent could be readily selected based on the patchy phenotype from DTC migration defects.
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From these landscape models, compounds forming complex activity cliffs can be readily selected.
Therefore, newly arising guanidine-resistant virus could be readily selected during guanidine treatment in mice infected with poliovirus.
This is consistent with the results in mice, in which guanidine-resistant variants were readily selected.
These regions were selected based on a prior study showing that occlusions of these segments were more likely to be associated with larger strokes [18] and based on the likelihood that proximal occlusions in these locations could be readily identified by physicians with minimal training in interpreting CTAs.
The students were selected based on test scores.
Wells were selected based on their use.
Committee chairs are selected based on seniority.
Antibodies were selected based on known performance.
Variables are selected based upon the Bayesian Information Criterion BICC).
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