Sentence examples for be rationally engineered to from inspiring English sources
These data reveal that pdgs can be rationally engineered to retain full catalytic activity, while dramatically altering mechanisms of target site location.
Therefore, the next section will discuss that how various physicochemical properties of nanomaterials can be rationally engineered to influence their biomedical potential to achieve desired biological goal without any toxicological impact.
We have demonstrated that IPK can be rationally engineered to accept and phosphorylate oligoprenyl monophosphate substrates, such as FP.
The stability of the best enzyme was then increased by semirational mutagenesis, after which its active site was rationally engineered to enable the binding of polyphenolic acceptors.
Thus, the redesigned hCE1 compares favorably to other mammalian enzymes that have been rationally engineered to improve hemi-substrate metabolism (Table 4).
By stabilizing the nucleating foldon, Im9 was rationally engineered to fold through a kinetic intermediate, while retaining the transition state structure of the homologous Im7 domain [ 48].
Complex phenotypes, such as strain tolerance to toxic compounds, are difficult to be rationally engineered due to the limited knowledge about molecular mechanism.
Nevertheless, after their synthesis their surface chemistry needs to be rationally engineered, in order to warrant colloidal stability in biological milieu, as well as to keep their bioactivity.
In synthetic biology applications, biosynthetic modules from secondary metabolic processes can be rationally engineered and combined to produce either new compounds, or to improve the activities and/or the bioavailability of the already known ones.
In this way, we may gain new insights into the ways in which the properties of toxins could be rationally engineered (for example, to generate novel toxins with therapeutic applications).
The unanswered questions are discussed to guide future research directions, and facilitate progress in this area so that the materials can be rationally engineered during synthesis and processing to yield new materials with enhanced properties for a number of applications.
