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Furthermore, the heat capacity changes (Δ C p °) associated with the ligand binding to HDAC8 markedly differed from one SAHA analogue to the other, and such features could primarily be rationalized in light of the dynamic flexibility in the enzyme structure in conjunction with the reorganization of the active site resident water molecules.
Furthermore, the magnitudes of the proton inventory, intrinsic enthalpic changes, and heat capacity changes associated with the enzyme ligand complexes significantly differed from one SAHA analogue to the other, and such differences could not be rationalized in light of the structural differences among the ligands and/or their plausible complexes with the enzyme.
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The understanding of the decay process is rationalized in light of the interplay between spectroscopic and electrochemical techniques.
This can be rationalized in terms of availability of active sites on TiO2 surface and the light penetration of photoactivating light into the suspension (Neppolian et al. 2002b).
Such a condition can be rationalized in two possible ways.
Stable isotope fractionation (e.g., D/H) can also be rationalized in this manner.
The enhancement of the degradation rate with addition of H2O2 can be rationalized in terms of several reasons.
(2) SAR transfer can be rationalized in different ways.
The effect of mutations affecting the enzymatic properties of AGT can be rationalized in structural terms.
The different buckling behaviors, dependent on the constituent phases, are rationalized in the light of the disparity in mechanical properties.
So the unjust was rationalized in service of safe streets.
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