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Therefore, the application of IGF-1R overexpression may be rational to predict clinical prognosis in operable cervical cancer.
Generally, it might be rational to predict the signal transduction activated by a proteasome inhibitor to be due to proteasome inhibition, then endothelium reticulum (ER) stress and finally apoptosis.
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It is therefore rational to predict that the further upregulation of HIF-1 α by an anaesthetic would compound or even enhance its effect of promoting malignant behaviour in cancer cells, whereas the use of an agent such as propofol which has been shown to inhibit HIF-1 α activity might prove helpful in bringing about the opposite effect.
Thus, it is not very rational to predict for each region that plant landscape will completely change, but on the contrary, one must take into consideration the fact that some modifications can have an incidence on the pollinosis: the Cypress (Cupressus sempervirens) could become allergenic out of the Mediterranean zone.
It is rational to hypothesise similar benefits in cardiopulmonary bypass.
The yield function for material yielding incorporated in the stiffness formulation, which allows for both axial force and bending moment effects, is more accurate and rational to predict the behaviour of the frames under fire.
The similarity criteria developed in this study are verified and prove to be rational and efficient in predicting erosion in engineering through model experimental design.
To avoid the economical, environmental and social impacts due to pipeline collapse, rational methodologies should be employed to predict the safe life of corrosion affected steel pipes and to instigate maintenance and repairs for the corroded pipeline system.
Our findings validate the new model of CYP24A1, which can now be used to predict structural modifications for rational vitamin D drug design.
During the hypo manic phase, chewers may not be capable of rational judgment and they also may not be able to predict the serious consequences of their actions.
Thus, a rational approach is required to predict the residual strength after cover-spalling.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com