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Dementia severity will be rated using the Functional Assessment Staging (FAST) [ 36].
White matter hyperintensities (WMH) at baseline will be rated using the Scheltens scale (range, 0 to 84 points) [ 62].
(a) Presence of side-effects: Any toxicity will be rated using the National Cancer Institute Common Terminology Criteria for Adverse Events (NCI CTC AE) v3.0 [ 24].
To assess therapist competence in CBT, a random sample of audiotaped sessions will be rated using the Cognitive Therapy Rating Scale (CTRS).
Radiographic disease severity will be assessed from the baseline x-ray using the Kellgren and Lawrence grading system [ 21] while individual features of osteophytes and joint space narrowing will be rated using the Osteoarthritis Research Society International Grading system [ 22].
In the field of cognitive behaviour therapy (CBT), for example, common practice is for treatment sessions to be rated using the Cognitive Therapy Scale (CTS; Young & Beck, 1980 , 1988 or its revised version (CTS-R; Blackburn, James, Milne, & Reichelt, 2001).
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The severity of depression was rated using the Montgomery Asberg Rating Scale (MADRS) for clinical rating 33 and self-rating (MADRS-S) 34.
Each patient was rated using the 8-point Precise Diagnostic Score score, composed of a clinical score (0-4 points) and an imaging score (0-4 points).
In addition, symptom severity at baseline was rated using the Mini-Mental Status Exam, Hamilton Depression Rating Scale, Hamilton Anxiety Scale, Bech mania scale, Unified Parkinson Disease Rating Scale UPDRSS), and Barnes akathisia scale.
Team performance was rated using the TEAM tool.
Clinical evaluation was rated using the Neck Disability Index (NDI) and the visual analog scale (VAS).
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