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With respect to glaucoma, drug or placebo drops would be randomly administered and IOP would be recorded.
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The questionnaires were randomly administered to children and parents during follow-up visits at the six participating centers with proved experience in pediatric type 1 diabetes management and belonging to the Italian Society of Pediatric Endocrinology and Diabetes (ISPED) (Catania, Florence, Genoa, Naples, Rome, Turin).
Repeated extraction doses of 10, 100, and 1,000 mg/kg/day were randomly administered to both male and female Sprague Dawley rats for 12 months.
Seven inspiratory NO concentrations were randomly administered: 0.15, 0.45, 1.5, 4.5, 15, 45 and 150 ppm.
Using the same ventilatory settings as in phase 1, seven inspiratory tracheal concentrations of NO, chosen according to a logarithmic scale, were randomly administered: 0.15, 0.45, 1.5, 4.5, 15, 45 and 150 ppm.
Adrenaline or milrinone were randomly administered to achieve a cardiac index > 3 l/min/m2 and were maintained thereafter for the 14-hour study period.
After 48 h, these mice were randomly administered injections of PBS, free ADR, PC-ADR-BSA, and PC-ADR-Fab for three times once a week.
Four versions of the scenario were randomly administered, varying based on the nature of the conflict and the level of intimacy with the conflicting party: disagreement (intimate), competition for resources (intimate), disagreement (recently acquainted), and competition for resources (recently acquainted).
In a parallel design, 23 and 22 healthy pre-menopausal women were randomly administered a contraceptive vaginal ring (CVR) delivering 150/15 μg Nestorone®/ethinyl estradiol (EE) daily or an oral contraceptive (OC) containing levonorgestrel and EE (150/30 μg) for three cycles, to compare the effects on C-reactive protein and other markers of inflammation.
The antibiotics were randomly administered in the tibial intraosseous cannula in half of the animals and in a peripheral intravenous cannula (ear vein) in the other half in a non-blinded manner.
Using a crossover design, inferior alveolar nerve blocks were randomly administered, in a double-blind manner, using 4% articaine with 1 100,000 epinephrine and 2% lidocaine with 1 100,000 epinephrine, at two separate appointments, to 57 subjects.
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