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The initial target enrollment was 12 patients; three patients were to be randomized to four dose cohorts.
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Participants will be randomized to two arms, the control arm and BCM arm.
After providing written informed consent, eligible patients will be randomized to two treatment strategies.
Eligible G6PD-normal patients will be randomized to two primaquine regimens and the control arms in a ratio of 2 2 1.
Subjects will be randomized to two groups (intervention or CAU) after completion of the baseline assessment (online questionnaires and clinical interview via telephone).
Twenty subjects were to be randomized to two groups of ten each; however, the trial concluded after six subjects were enrolled due to a preference among them for enrolling in other MCI studies, including drug trials.
Animals were randomized to four groups (n=6 mice/group) for treatment.
As shown in Fig. 1, patients enrolled in the trial were randomized to four treatment arms.
Participants were randomized to four different groups as they were recruited by the researcher (using a randomization sequence [ 9]).
The rats were randomized to four study groups based on their body weights on the day before surgery.
Twelve Sprague-Dawley rats were randomized to four groups: control (defect only), decellularized bone matrix (DECBM), and HGCS with and without multipotent adult progenitor cells (MAPCs).
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