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These patients that meet the inclusion criteria will be randomized into either a treatment group or a placebo group.
Seventy subjects post primary total hip arthroplasty will be randomized into either an experimental group (n=35), or to a control group (n=35).
In accordance with the principles of a patient preference trial, only patients who do not have a strong group preference will be randomized into either the exercise or the control group using the RITA randomization software (STATSOL.de) [ 19- 21].
This trial will recruit 30 persons with MS across central Illinois who have an Expanded Disability Status Scale score between 4.0 and 6.0, and those persons will be randomized into either the intervention or control arm of the study; the participants will not be blinded regarding group assignment.
After baseline assessments, classes will be randomized into either the experimental or the control group.
Patients will be recruited, cleared for participation, receive an initial assessment, and then be randomized into either the ILI group or the DLI group.
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As opposed to other randomized controlled trials in which participants are randomized into either a treatment- or control group, we therefore believe that this design may keep participants blinded for group allocation.
Methods: A design with four groups was employed; the participants were randomized into either a placebo group, a natural history group, or into two nocebo groups.
Individuals were randomized into either an intervention group that received standard exercise and nutrition information plus up to five face-to-face counseling sessions over 6 months, or into a control group that only received the standard information.
Patients (n = 86) undergoing lumbar spinal surgery were randomized into either an Intervention group (using educational intervention; n = 43) or a Control group (n = 43); four patients voluntarily dropped out after surgery (one in Intervention group; three in Control group).
Women were randomized into either intervention or control group.
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