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Protection against exonucleases can be provided by modifications at the 5′ caps (such as PEG adducts) and 3′ ends (e.g., by addition of a 3′-3′-linked thymidine cap) to increase aptamer retention time in the blood [ 47].
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Boron Neutron Capture Therapy (BNCT) project in Tehran Research Reactor (TRR) is currently ongoing and an appropriate neutron beam for BNCT has been provided by modification of TRR thermal column.
This protection may be provided by HVO_0794, which encodes a Zim CTAG modification methylase.
A qualitative, visual method to explore the potential for subgroup effects was provided by a modification of the forest plot, i.e., adding a vertical axis indicating the proportion of a subgroup variable in the individual trials.
As Myc activity directly correlates with protein expression, further complexity is provided by post-translational modifications that regulate Myc in normal stem cells or deregulate it in malignant stem cells.
A further level of PP2A regulation is provided by post-translational modification of the catalytic subunit, which can be phosphorylated on Tyr307, as well as on a threonine residue [17], [18].
A synthetic view of the biological role of histone modifications is provided by the histone code hypothesis [ 1].
Dynamic feed rate modification is provided by superposing our own design of a fast feed system driven by a piezoelectric actuator to the conventional feed drive of the CNC machine tool.
Evidence for surface modification was provided by electrochemical reductive desorption of the monolayer and ellipsometry, consistent with a coverage of 2.5 × 10−10 mol cm−2 and a thickness of 13 Å, respectively.
For 1-butene, the best prediction was provided by the Yen and McKetta modification of the RST, whereas for carbon monoxide and hydrogen it was necessary to include a mixing entropy term in the RST.
The most intriguing example for chromatin modification is provided by Ctf18-RFC – whose function is critical to establish sister chromatid pairing during S-phase [10], [11], [15].
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