Sentence examples for be protective in models from inspiring English sources

Injected biliverdin hydrochloride (BV), which is rapidly converted to bilirubin in vivo [31], has been shown to be protective in models of cardiac transplant rejection [31], vascular intimal injury [32], and sepsis-induced acute lung injury [33].

Our results indicate that Gilz might also be protective in models of acute inflammation, such as endotoxemia.

Cyclosporine A and FK506 have been shown to be protective in models of TBI, at least in part by reducing mitochondrial dysfunction and traumatic axonal injury [ 118- 122].

Previous studies have reported that pretreatment with NAC is protective in models of cardiac arrest.

Dejager et al. reported that blockade of type I IFN signaling was protective in models of endotoxin and CLP-induced severe sepsis [ 35].

Some report that IL-10 actually impairs host defense against S. pneumoniae (50, 52), whereas others report that IL-10 is protective in models of septic peritonitis (49).

Conversely, we found that the divalent metal chelator, Calcium Disodium Ethylenediaminetetraacetic acid (CaEDTA) reduces iron and zinc levels in C. elegans, is protective in models of proteotoxicity, and extends lifespan.

Although Wlds is protective in models of axonal severing [ 9] and a number of other disease models [ 12- 14], it fails to protect against all forms of axonal degeneration in disease models [ 15- 17] and does not protect against axon degeneration that occurs in developmental axon pruning [ 18].

Importantly, the inhibition of DRP1-induced fragmentation has been shown to be protective in physiological models of disease, including Parkinson's disease 57, 58 and ischemia-reperfusion injury models 52, providing hope for future therapeutic development.

P2X7 knockout mice showed a lack of hypersensitivity to mechanical and thermal stimuli [30, 31] and P2X7-specific antagonists have consistently been shown to be protective in animal models of inflammatory [32 34] and neuropathic pain [33, 35].

Inhibitors of sirtuin-2 deacetylase (SIRT2) have been shown to be protective in various models of Huntington's disease (HD) by decreasing polyglutamine aggregation, a hallmark of HD pathology.