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First, it allows the maintenance of distinct and robust transcriptional states, which could potentially be propagated through cell division, and therefore act as epigenetically inherited features.
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Xist RNA is thought to recruit silencing factors that modify the chromatin, bringing about a mitotically stable heterochromatic configuration that can be propagated through subsequent cell divisions (reviewed in [ 2]).
bTwo recent reports do suggest that AD pathology can be propagated through prion-like cell-to-cell spread in mice following injection of brain homogenates from AD transgenic animals [ 100] or an AD patient [ 101].
Foreign genes introduced during zygotic or embryonic development will be propagated through mitosis into germ cells and, therefore, next generation.
ESCs are derived from early mammalian embryos and can be propagated through apparently unlimited, undifferentiated proliferation (self-renewal) in cultured cell lines (mouse: [ 5, 6], human: [ 7]).
Therefore, we can investigate the progression of gene expression of these cells independent of outside stimuli which may be propagated through endocrine or neurological signaling.
Cells can sense several stimuli, both internally and externally, and the received information will subsequently be propagated through a cascade of physico-chemical signals.
Why should disappointment be propagated through another generation, a cruel snap travelling down an endless rope?
The waves are propagated through the cell mass by cAMP-induced cAMP production, also known as cAMP relay.
A light pulse containing light of wavelengths 300 900 nm was propagated through the simulation cell.
IL-6 signaling is propagated through either direct cell membrane receptor signaling or soluble receptor trans-signaling (TS).
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