Determining the order of closely linked markers is prone to sampling error, and QTL mapping is sensitive to the order of markers (Broman and Sen 2009).
Currently, the only method to quantify diffuse fibrosis is invasive biopsy, which carries significant morbidity, is prone to sampling error and fibrotic involvement of the whole left ventricle cannot be determined [7].
The current clinical standard of repetitive invasive endomyocardial biopsies is prone to sampling error, entails a risk of severe complications, causes discomfort and anxiety for the patients and, unlike for kidney transplants, is usually performed as a last resort.
Likelihood-based parameter inference from Markov chain Monte Carlo is prone to sampling bias [26], [29].
In addition, these results highlight the shortcomings of current vector detection methods: the need to acquire multiple biopsies using an invasive procedure that is prone to sampling error and is concomitantly impractical for repeated monitoring of the entire tumor.
Therefore, liver biopsy is prone to sampling errors and to intraobserver and interobserver variability [ 17, 18].
Biopsy is prone to sampling error and may incorrectly indicate benign disease or miss early invasion.
Thus, they are prone to sampling errors and are limited in their extrapolation to the general population [ 13].
Flow cytometry reflects a larger, more representative sampling of tissue macrophage content, whereas histological approaches are prone to sampling error.
However, such a frequency-dependent coding strategy is prone to sampling bias if sample sizes of character statement assessment are low [ 59], as in the present study.
