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Natural products with industrial applications can be produced from primary or secondary metabolism of living organisms (plants, animals or microorganisms).
The idea that piRNAs can be produced from primary transcripts or from mRNAs is supported by a correlation analysis, which found that more piRNAs are produced by more highly expressed genic transcripts [ 77].
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Pre-miRNAs are produced from primary pri-miRNAs transcribed from miRNA genes by RNA polymerase II.
All microarray data of examined tissues were produced from primary surgical cases without chemotherapy.
MiRNA/miRNA* duplexes, which contain the mature miRNA, are processed from pre-miRNA which is produced from primary miRNA [ 6].
Essentially linear alcohols, also known as oxo-alcohols, are produced from primary alcohols derived from branched butylene oligomers.
MiRNAs are produced from primary miRNAs (pri-miRNAs) and precursor miRNAs (pre-miRNAs) by DICER LIKE 1 (Dcleavageavage [ 14, 15].
Plant miRNAs are produced from primary transcripts (pri-miRNAs) that form a miRNA/miRNA*-containing stem-loop structure.
EpiAirway™ tissue cultures (AIR-100), purchased from MatTek Corporation, were produced from primary bronchial epithelial cells obtained from a 23-year-old male donor with no history of smoking.
MiR171h has later been predicted to be produced from an 811 bp long primary transcript encoding two miR171h loci on a single arm of its fold-back structure [[ 31]].
The fact that highly abundant siRNAs were mapped at positions that are very close to each other (see below) is consistent with the notion that the primary siRNAs may be produced from such a limited place.
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