Sentence examples for be processed to active from inspiring English sources

To assess whether B. recurrentis-attached PLG can be processed to active plasmin, spirochetes were pre-treated with PLG and subsequently incubated with the exogenous human plasminogen activator uPA.

Upon larval ingestion, the crystalline inclusions dissolve in the alkaline pH of the insect's gut, releasing Cry and Cyt protoxins that will be processed to active toxins by insect gut proteases [ 1].

Interestingly, p62 also participates in the synthesis of neoantimicrobial peptides, by bringing inactive precursors such as Fau to autophagic degradation, where they are processed to active fragments [ 91]. p62 is also involved in the regulation of apoptosis.

Classically, IL-1 β is synthesized as a precursor of IL-1 β (pro-IL-1 β) by blood monocytes, tissue macrophages and dendritic cells after activation by pro-inflammatory stimuli such as IL-1, TNF or TLR ligands and needs to be processed to be active.

Similar findings were observed when recombinant HcpA was coated onto microtiter plates supporting the notion that HcpA-bound PLG can be processed to stable functional active plasmin (Fig. 7B).

Moreover, the monomeric cystatin F in dense lysosomal vesicles and those harbouring cathepsin C in murine mast cells appeared to be processed to the truncated active form.

Silencing caspase-10 prevented processing of caspase-2, whereas caspase-8 was processed to its active subunits, and silencing of caspase-8 did not prevent the processing of caspases-10 and -2.

Caspases-2 and −10 were processed to their active subunits following co-treatment, whereas caspase-9 processing was not detected.

Finally, we also found that Bid (GeneID: 12122), a potential mediator of LMP-mediated cell death [24], [60], [61], is processed to its active form, tBid, in the presence of LT (Figure 5B).

Nevertheless, pro-caspase-3 is processed to its active subunits only in cells with an intact mitochondrial apoptotic-signaling pathway.

The caspase activity induced by co-treatment was not affected by silencing caspase-2 expression and caspases-8 and -10 were processed to their active subunits.