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And purchasing a watch on eBay could be problematical, because it is often unclear who the seller is.
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But air has to be rendered through indirection, and earth is problematical because it has meanings of different depths.
However, interpretation of these data is problematical because although SB203580 has the stress-activated kinases p38 and JNK1/2 as its preferred targets, it does show relatively low overall kinase selectivity.
However, rigorous testing of this hypothesis has been problematical because the cell wall is normally an essential structure.
Response assessment by conventional radiographic methods is problematical because treatment induces fibrosis and makes tumour measurements difficult.
Correcting for selection bias in genome scans is problematical because no unbiased estimator exists for the scan data alone.
This type of restricted image use is problematical because experimental work on the nature of concepts suggests that they are best understood as encoding information about both the prototype of the conceptual category, and examples of variation around this prototype (Wisniewski 2002).
While this is understandable, given the need to act and make a difference, and thus reduce complexities to concrete activities ("Let's get on, we're doing responsible development, we're OK"), it can be problematical, already because of the lock-ins (i.e. path dependencies) while society (and technology) change.
Determining BF and best ITD from multiunits is extremely problematical because it is not guaranteed that the underlying neurons all have the same tuning.
Determining BF and best ITD from multi-units is extremely problematical because it is not guaranteed that the underlying neurons all have the same tuning.
"You're assuming every market would take it," Palansky said, "but it would be problematical in those secondary markets.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com