Sentence examples for be problematic to assign from inspiring English sources

Microarrays can reliably detect cRNA species at the concentration of a few pico-molars, but it can be problematic to assign a certain gene expression event to the correct cell subpopulation of complex tissues.

While it is problematic to assign ancestral versus derived states to gene duplicates originating from WGD events, we reasoned that a paralog within an ohnolog pair could be characterized as being ancestral-like or derived-like based on the extent of gene-neighborhood conservation it shared with a single-copy ortholog in an outgroup genome.

It was problematic to say the least.

Use of death certificates may be problematic for assigning a single cause of death, especially among the oldest women who often have multiple medical problems.

But she stressed that, regardless of evidence, it's problematic and counterproductive to assign blame to one person or one region for the virus's spread.

As a result, it trims the various sequences at an approximately equal length, reducing the length of the longer sequences; this can therefore be problematic when taxonomy is assigned using a minimal percent of similarity with the reference sequences.

Mapping reads back to more similar sequences to estimate abundances would be problematic because reads could not be uniquely assigned to a particular sequence.

Because noisy junctions may result in incorrect assembly results, a higher positive cost is assigned for junction edges that are more likely to be problematic.

Before today, app ratings on Google were somewhat problematic because developers were able to assign them by themselves.

Rubio's lieutenants proved to be problematic.

They turn out to be problematic.