Sentence examples for be problematic to assemble from inspiring English sources
Insect genomes can be problematic to assemble, due to combinations of high polymorphism, inability to breed for genome homozygocity, and small physical sizes limiting the quantity of DNA able to be isolated from a single individual.
However, the genome draft assembly at present has a total size of 473 Mbp, while the haploid genome size estimated by flow cytometry is 1.3 Gbp [ 75], indicating that some regions are problematic to assemble from short reads and are missing in the assembly.
It is problematic to reconstruct long repetitive regions by assembling reads shorter than the repetitive regions.
The implications for ExxonMobil are problematic, to say the least.
> -wrap-foot> The length dependence of fragment classification methods in particular can be problematic if partially assembled data have to be analyzed.
However, the current nanopore technology still has limitations with respect to error-rate, and this is problematic when attempting to assemble whole genomes without secondary rounds of sequencing to correct errors.
In addition, the massive amount of short metagenomic sequence reads (between 20 and 700 bases depending on the platform) can be problematic for assembling and identifying complete coding DNA sequence and/or operon structure.
