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"It was a beautiful project with a humanitarian aspect but I understand that being the president's partner and working for a television channel may be problematic or even fuel suspicion for some people," the 47-year-old Trierweiler said.
Because using one figure indicative for the quality of included studies has been shown to be problematic or even misleading, the numbers were not included in the final analyses (17).
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For instance, in patients with strongly reduced initial creatinine clearance adequate high-dose chemotherapy is problematic or even impossible because of the increasing risk of a further loss of renal function.
The process of reproduction is simple yet strewn with complex processes, any one of which can be problematic and even catastrophic to the fetus or mother.
To do so with no thought or preparation for our loved ones can be problematic and even irresponsible.
But 'truth telling' alone can be problematic and even hurtful when it's not aligned with being helpful or kind.
Wayne discouraged him from acting rashly, as fugitives can be problematic collaborators, even for intelligence agencies.
In a country with limited freedom of expression, speaking in public can be problematic - even if it is just to make people laugh.
Estimating p(D) can be problematic and even impractical.
Such generic interpretations may be problematic, as even small improvements may be important in health-related contexts.
This, however, requires very accurate coregistration of PET and CT/MRI which can be problematic even for modern PET/CT or PET/MRI systems due to patient motion during measurement.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com