Sentence examples for be problematic in that from inspiring English sources

The latter could be problematic in that persistent microglia activation can exert long-term deleterious effects on neurons and behavior.

This can be problematic in that mRNA expression does not always correlate with protein expression.

This could be problematic in that the prognosis of early AKI may differ from that of late AKI.

Such clumping can be problematic in that it makes it difficult to apply a uniform coating of the discharge cartridges, potentially leading to inconsistent results.

Using epidemiology alone to define dietary reference intakes (DRI) would be problematic, in that such reference values target risk reduction for a particular chronic disease (Russell, 2008).

This type of preservation bias could be problematic in that amber fossils cover a shorter time window than compression-impression fossils.

This is problematic in that the effects of any proposed change on equality of access are not always straightforward and the positive effects of other variables may outweigh the negative effects.

Such differences are problematic in that the conservation of mass principle is violated.

"The president's budget is problematic in that regard," Ms. Napolitano said.

In other cases, we saw that using the LCD was problematic in that it would not display correctly.

The term non-vibrato is problematic in that it is not possible for a human to sing a tone without fundamental frequency variation.