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The reason is the tight amount of degrees of freedom in which this analysis is conducted, which would be problematic in case of estimating Eqs.
Shutdown of ADS operating at high levels of sub-criticality, (i.e. keff ∼0.99), without the support of reactivity control systems (such as control or safety rods), may be problematic in case the ability of cooling of the core should be impaired (i.e. loss of coolant flow).
Add that to the fact that I would have to give up my Dutch passport, which would have been fine (I am about as Dutch as a load of English fools on a stag do smoking weed and shagging prostitutes in Amsterdam) — if it hadn't been for the fact that this would be problematic in case I would ever need to be at the receiving end of an inheritance from my parents.
When presenting the statistical results we start with the main effects and continue with interactions, which can be problematic in case of strong interactive effects.
Granger causality mappings (which are based on the concept of temporal precedence) might be problematic in case of strong inter-regional variability of the haemodynamic response (David et al., 2008), e.g. in stroke patients with vascular abnormalities.
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Diagnosis may be problematic in cases with long clinical interval with up to 30 years, being reported between completed treatment of Kala-azar and the appearance of skin lesions [ 16– 16].
In none of the institutes were routine management systems perceived by respondents to be problematic, but host institutions' regulation of reimbursement was thought to be problematic in cases where the institute was dependent upon the management policies of a parent organization.
Studies attempting to estimate Ne in other endangered avian populations also reported wide confidence limits (e.g., peregrine falcons (Falco peregrinus), 500 < Ne < 1000 [ 39]; yellow-eyed penguin (Megadyptes antipodes), 200 < Ne < 1000 [ 40], which may be problematic in cases where greater precision is needed for management decisions.
The subsequent feasibility study however indicates that the assumption of a lognormal distribution is problematic in case of fire.
It is now widely believed that the descriptive theory of names is not a satisfactory proposal in the case of fictions (like Pegasus), and that it is problematic in cases when we embed the descriptions in a certain class of intensional constructions.
Two disadvantages of K-means are that it requires the prespecification of the number of classes, which is not often known; furthermore, K-means create clusters based only on the first moment, which is problematic in cases where the variance of a specific probe contains biologically important information.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.
Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com